The PuffHouse e-cigarette does not involve combustion, but instead aerosolizes the liquid, which is a major difference.

PuffHouse devices, while not harmless, do not produce tar and are estimated to be 95% less harmful than combustible tobacco according to Public Health England.

While e-cigarettes are electronic devices that vaporize e-liquids with or without nicotine, a heated tobacco product (HTP) is a device specially designed to vaporize tobacco leaf sticks at a lower temperature than regular cigarettes, below 600°C. The heat creates an aerosol or smoke that needs to be inhaled. HTPs use built-in or external heat sources, heated sealed chambers, or customized product-specific rods. There are different types of HTP. The two most common designs are those that use an electric battery to heat the tobacco leaf sticks, and those that use charcoal that is ignited and then heats the tobacco.

Smoking combustible cigarettes involves burning dried tobacco leaves to create inhalable smoke, and it is this burning that creates toxic substances that lead to illness, disease and death.

While both PuffHouse E-Cigarettes and smoking can deliver nicotine. As Michael Russell, a scientist and pioneer in the study of tobacco addiction, once said, "People smoke for nicotine, but they die from tar," and tar is just what you won't find in PuffHouse devices.